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Cranial SolutionsNew Zealand

Evidence & references

Research & Citations

A curated index of peer-reviewed studies and medical literature on cranial and facial bone dynamics, cerebrospinal fluid flow, glymphatic drainage, dural mechanics, and related neurological conditions. Each entry links to the original PubMed, PMC, or journal source.

01

Cerebrospinal Fluid (CSF) Drainage & the Cribriform/Facial Axis

These papers document how CSF drains directly through the cribriform plate of the ethmoid bone into the nasal lymphatic pathway.

02

Glymphatic System, Meningeal Lymphatics & Intracranial Waste Clearance

Foundational studies detailing the brain's waste clearance pathways (glymphatics) and how meningeal lymphatic dysfunction exacerbates neuroinflammation and brain injury.

03

Cranial Sutures, Micro-Motion & Mechanical Stress

Research exploring the patency of adult cranial sutures, dural nerve endings within sutures, and biomechanical stress distribution across the cranial base.

04

Trigeminal Somatosensation, TMJ & Orofacial Neuromuscular Dysfunction

Studies linking TMJ pathology, cranial base structures, trigeminal nerve hyperactivity (CN V), and inflammatory biomarkers.

05

Sphenoid Mechanics & Neuroendocrine (Hormonal) Integration

Anatomical and endocrinological literature detailing how the sphenoid bone houses the pituitary gland and influences endocrine signaling.

06

Advanced Clinical Research: The Nasal-Brain Axis

Landmark discoveries showing that CSF waste clearance drains directly through the cribriform plate into the back of the nasal mucosa, linking nasal passage health to brain fluid clearance.

07

Dural Tension, Meningeal Stretch, & Migraine Pathology

Peer-reviewed studies on dural tension, dural stretch, meningeal nociception, and trigeminal migraine mechanics.

08

Dural Tension & Craniofacial Pain Mechanics

Research and clinical links focused on dural tension, meningeal mechanics, and head pain.

09

Post-Concussion (TBI/PCS) & Cranial Decompression

Literature on cranial mechanics, endonasal decompression, and post-concussion recovery.

10

Cranial Nerves & Neurological Dynamics

Research detailing the mechanical pathways of the facial nerve through the temporal/sphenoid region, dural tension, and cranial decompression.

11

Glymphatics & Neurodegeneration

Studies showing how impaired cerebrospinal fluid flushing contributes to toxic protein accumulation, and how musculoskeletal alignment in the head and neck influences this drainage network.

12

Osteopathy & Glymphatic Fluid Clearance

Peer-reviewed studies linking osteopathic manipulative treatment, cranial manipulation, and manual therapy protocols to glymphatic function, CSF circulation, and metabolic waste clearance.

13

Sacro Occipital Technique (SOT) & Pelvic Dynamics

Published research connecting SOT, pelvic blocking, and craniosacral dynamics - the biomechanical relationship between the sacrum and the occiput.

14

Postural Adaptations & Airway Mechanics

Scientific studies examining how mouth breathing alters head posture, cervical spine alignment, and respiratory mechanics.

15

Sphenoid Mechanics & Mouth Breathing Dynamics

Cephalometric and orthodontic literature connecting mouth breathing, bone position, sphenoid metrics, and skull base alterations.

16

Airway Obstruction & Mandibular Posture

Research on the relationship between mouth breathing and mandibular retrusion - low tongue posture, loss of palatal support, and backward jaw rotation.

17

Sinus Congestion & Structural Airway Collapse

Research examining the relationship between chronic sinus congestion, mucosal inflammation, and structural nasal collapse such as nasal valve collapse, septal deviation, and turbinate hypertrophy.

18

Cranial Bone Mechanics & Sensory Nerve Dynamics

Research on how cranial or facial bone shifts can narrow the bony exit channels of the skull base, compressing sensory nerve fibers of the trigeminal nerve (CN V).

19

Post-Nasal Drip & Nasal Bony Architecture

Research on how the position of the maxilla, sphenoid, vomer, and palatine bones dictates sinus drainage slopes and nasal cavity volume.

20

Nasal Obstruction & Skeletal Adaptation

Research examining how nasal airway obstruction directly drives structural shifts in the craniofacial bones, including maxillary constriction, palatal height changes, and cranial base angle adaptations.

These references are provided for education. They describe published research into anatomy and physiology; they are not a promise of any individual treatment outcome. Whether Nasal RX is suitable for you is determined only through an individual clinical assessment.

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